TSKS antibody (AA 121-170) (Biotin)

Catalog No. ABIN1391131

This Rabbit Polyclonal antibody specifically detects TSKS in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for TSKS antibody (AA 121-170) (Biotin) (ABIN1391131)

Target: TSKS (Testis-Specific serine Kinase Substrate (TSKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSKS antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TSKS Antibody (Biotin)

Binding Specificity: AA 121-170

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSKS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TSKS

Target: TSKS (Testis-Specific serine Kinase Substrate (TSKS))

Alternative Name: TSKS

Background:

Synonyms: STK22 substrate 1, Stk22s1, Testis specic kinase substrate, Testis specic serine kinase substrate, TSKS, TSKS1, MGC134104, TSKS_HUMAN.

Background: TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis.

Gene ID: 60385

Pathways: Toll-Like Receptors Cascades